Hanna Instruments (M) Sdn Bhd
11A, Jalan PJS 11/20,
Bandar Sunway,
46150 Petaling Jaya,
Selangor, Malaysia.
+603-5638 9940
+603-5638 9829
Penang Branch Office
Hanna Instruments (M) Sdn Bhd
N0. 303-2-27, Krystal Point,
Jalan Sultan Azlan Shah,
11900 Sungai Nibong,
Penang, Malaysia.
+604-638 4558
+604-645 4558
penang@hannamalaysia.com

Sabah Branch Office
Hanna Instruments (M) Sdn Bhd

No. 4-1, 1st Floor,
Plaza Kingfisher,
Jalan Plaza Kingfisher 5,
Inanam, 88450 Kota Kinabalu,
Sabah, East Malaysia.
088-382 941
088-382 942
sabah@hannamalaysia.com

Acidosis

Acidosis is an increased acidity in the blood and other body tissue (i.e. an increased hydrogen ion concentration). If not further qualified, it usually refers to acidity of the blood plasma.
 
Acidosis is said to occur when arterial pH falls below 7.35 (except in the fetus – see below), while its counterpart (alkalosis) occurs at a pH over 7.45. Arterial blood gas analysis and other tests are required to separate the main causes.
 
The term acidemia describes the state of low blood pH, while acidosis is used to describe the processes leading to these states. Nevertheless, the terms are sometimes used interchangeably. The distinction may be relevant where a patient has factors causing both acidosis and alkalosis, wherein the relative severity of both determines whether the result is a high or a low pH.
 
The rate of cellular metabolic activity affects and, at the same time, is affected by the pH of the body fluids. In mammals, the normal pH of arterial blood lies between 7.35 and 7.50 depending on the species (e.g. healthy human-arterial blood pH varies between 7.35 and 7.45). Blood pH values compatible with life in mammals are limited to a pH range between 6.8 and 7.8. Changes in the pH of arterial blood (and therefore the extracellular fluid) outside this range result in irreversible cell damage.

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